Spirulina side effectsSpirulina is not a medication but a totally natural product that can help maintain or restore good health. What are spirulina side effects? No side effects are usually observed when eating spirulina as long as they are cultivated and packaged in good conditions. FDA recognize spirulina GRAS (Generally Recognize As Save for human consumption) if cultivated and manufactured following strict conditions.

Precautions and safety concerns 

Spirulina is a food and has a long history of safe use, even at very high doses, this is why there are no recorded spirulina side effects. However there is a wide range in quality, due to the variety of cultivation countries, methods, and packaging. It is rare but spirulina can come from polluted lakes or ponds contaminated by organic waste or other substances that can eventually be toxic, then the spirulina side effects that can be observed are not coming from spirulina itself but from the contaminants that was in the environment it was cultivated in. This is why when you buy spirulina, it is important to buy a reputable brand of spirulina.

Who should AVOID eating spirulina?

1. Phenylketonuria 

People with the rare metabolic condition called phenylketonuria (PKU) (inability to metabolize the amino acid phenylalanine) should not take spirulina. Spirulina is rich in all amino acids, including phenylalanine.

2. Hemochromatosis

People with hemochromatosis (iron overload disease) should avoid taking spirulina as it is rich in iron (and Vit B12).

If you have an autoimmune disease, such as multiple sclerosis, rheumatoid arthritis, or lupus, you should not take spirulina as it could stimulate your immune system and make your condition worse.

Interactions with medications 

Spirulina experimental pond - Spirulina side effectsThere are no reports in the scientific literature to suggest that spirulina interacts with any conventional medications. 

However, it is possible that spirulina might interfere with drugs that decrease the immune system  (immunosuppressants).

Spirulina increase the immune system and therefore, might decrease the effectiveness of medications that decrease the immune system including: Adalimumab (Humira), azathioprine (Imuran), basiliximab (Simulect), corticosteroids (glucocorticoids), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), Etanercept (Enbrel), Infliximab (Remicade), Leflunomide (Arava), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), prednisone (Deltasone, Orasone), tacrolimus (FK506, Prograf), sirolimus (Rapamune), and others.

Interactions with herbs and supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.


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